HRID2210711

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：C=CCOC(=O)O[C@H](C)[C@H]1C(=O)N[C@@H]1OC(C)=O

HCID18604782

未命名化合物

HCID19379277

未命名化合物

PRODUCTS

生成物

结构：C=CCOC(=O)O[C@H](C)[C@H]1C(=O)N[C@@H]1[C@@H]1CCC[C@@H](O[Si](C)(C)C)C1=O

HCID57026143

未命名化合物

HCID57103704

未命名化合物

PROCEDURE

实验过程

Using (3R,4R)-4-acetoxy-3-[(R)-1-(allyloxycarbonyloxy)ethyl]azetidin-2-one and 1,2-bis(trimethylsilyloxy)-2-cyclohexene, the procedure of Reference Example 3 was otherwise repeated to give (3S,4R)-3-[(R)-1-(allyloxycarbonyloxy)ethyl]-4-[(1S,3R)-2-oxo-3-trimethylsilyloxycyclohexan-1-yl]azetidin-2-one (S-compound) and (3S,4R)-3-[(R)-1-(allyloxycarbonyloxy)ethyl]-4-[(1R,3S)-2-oxo-3-trimethylsilyloxycyclohexan-1-yl]azetidin-2-one (R-compound), each as a colorless oil.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-0c7f1172ffeb4b8b8fcb2189530233d4
来源数据集: uspto-grants-1995_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05459260
来源说明: uspto-grants-1995_10

反应 SMILES

C(O[C@H:5]1[NH:8][C:7](=[O:9])[C@@H:6]1[C@H:10]([O:12][C:13]([O:15][CH2:16][CH:17]=[CH2:18])=[O:14])[CH3:11])(=O)C.[CH3:19][Si:20]([CH3:34])([CH3:33])[O:21][CH:22]1[CH2:27][CH2:26][CH2:25][CH:24]=[C:23]1[O:28][Si:29]([CH3:32])([CH3:31])[CH3:30]>>[CH2:16]([O:15][C:13]([O:12][C@@H:10]([C@@H:6]1[C@@H:5]([C@@H:24]2[CH2:25][CH2:26][CH2:27][C@@H:22]([O:21][Si:20]([CH3:33])([CH3:19])[CH3:34])[C:23]2=[O:28])[NH:8][C:7]1=[O:9])[CH3:11])=[O:14])[CH:17]=[CH2:18].[CH2:16]([O:15][C:13]([O:12][C@@H:10]([C@@H:6]1[C@@H:5]([C@H:27]2[CH2:26][CH2:25][CH2:24][C@H:23]([O:28][Si:29]([CH3:32])([CH3:31])[CH3:30])[C:22]2=[O:21])[NH:8][C:7]1=[O:9])[CH3:11])=[O:14])[CH:17]=[CH2:18]