3,5-Dibromotoluene → 1-(Benzo[b]thiophen-2-ylmethyl)-3-bromo-5-methylbenzene

HRID 221075Notes

Reaction equation

HRID 221075 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH3:9])[CH:5]=[C:6]([Br:8])[CH:7]=1.[S:10]1[C:14]([CH:15]=O)=[CH:13][C:12]2[CH:17]=[CH:18][CH:19]=[CH:20][C:11]1=2>>[S:10]1[C:14]([CH2:15][C:2]2[CH:3]=[C:4]([CH3:9])[CH:5]=[C:6]([Br:8])[CH:7]=2)=[CH:13][C:12]2[CH:17]=[CH:18][CH:19]=[CH:20][C:11]1=2

Participants

3

Reactant 2

HCID 153613,5-DibromotolueneHCID 7365001-Benzothiophene-2-carbaldehyde

Product 1

HCID 666066491-(Benzo[b]thiophen-2-ylmethyl)-3-bromo-5-methylbenzene

Procedure

3,5-Dibromotoluene and benzo[b]thiophene-2-carboxaldehyde were treated in a manner similar to Reference Example 1 to give the target compound.

Workup

  1. customto give the target compound

Sources & evidence

ORD record
ord-d911d48ccd0f432e99a1f6be21cf4ee6
Source dataset
uspto-grants-2012_06
Patent number
US08202984B2

Reaction notes

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