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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 221077Generated: October 26, 2026

7-Methyl-1-benzothiophene → 5-Bromo-2-chloro-1-(7-methylbenzo[b]thiophen-2-ylmethyl)benzene

https://huagongshe.com/reaction/221077

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-Methyl-1-benzothiopheneHCID 6428541—
Reactant5-Bromo-2-chlorobenzaldehydeHCID 10608925—
Product5-Bromo-2-chloro-1-(7-methylbenzo[b]thiophen-2-ylmethyl)benzeneHCID 66608160—

Reaction Steps

7-Methylbenzo[b]thiophene (see Tilak, B. D. Tetrahedron 9 (1960) 76-95) and 5-bromo-2-chlorobenzaldehyde obtained in Reference Example 16-(1) were treated in a manner similar to Reference Example 7 to give the target compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08202984B2
Source datasetuspto-grants-2012_06
ORD IDord-b6591011e40544428ef0c00325396538
Source noteuspto-grants-2012_06