1,3-Dibromo-5-chlorobenzene → 1-(Benzo[b]thiophen-2-ylmethyl)-3-bromo-5-chlorobenzene

HRID 221084Notes

Reaction equation

HRID 221084 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Br:8])[CH:5]=[C:4](Br)[CH:3]=1.[S:10]1[C:14]([CH:15]=O)=[CH:13][C:12]2[CH:17]=[CH:18][CH:19]=[CH:20][C:11]1=2>>[S:10]1[C:14]([CH2:15][C:4]2[CH:3]=[C:2]([Cl:1])[CH:7]=[C:6]([Br:8])[CH:5]=2)=[CH:13][C:12]2[CH:17]=[CH:18][CH:19]=[CH:20][C:11]1=2

Participants

3

Reactant 2

HCID 846761,3-Dibromo-5-chlorobenzeneHCID 7365001-Benzothiophene-2-carbaldehyde

Product 1

HCID 666083601-(Benzo[b]thiophen-2-ylmethyl)-3-bromo-5-chlorobenzene

Procedure

1-Chloro-3,5-dibromobenzene and benzo[b]thiophene-2-carboxaldehyde were treated in a manner similar to Reference Example 1 to give the target compound.

Workup

  1. customto give the target compound

Sources & evidence

ORD record
ord-65ace3fae7c6431ab40259f37471cba4
Source dataset
uspto-grants-2012_06
Patent number
US08202984B2

Reaction notes

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