5-Bromo-2-fluorobenzaldehyde → HCID 66608823, compound

HRID 221094Notes

Reaction equation

HRID 221094 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[S:9][CH:10]=[CH:11][CH:12]=1.[Br:13][C:14]1[CH:15]=[CH:16][C:17]([F:22])=[C:18]([CH:21]=1)[CH:19]=O>>[Br:13][C:14]1[CH:15]=[CH:16][C:17]([F:22])=[C:18]([CH2:19][C:10]2[S:9][C:8]([C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[F:1])=[CH:12][CH:11]=2)[CH:21]=1

Participants

3

Reactant 2

HCID 7363275-Bromo-2-fluorobenzaldehydeHCID 22146057HCID 22146057, compound

Product 1

HCID 66608823HCID 66608823, compound

Procedure

2-(2-Fluorophenyl)thiophene obtained in Reference Example 66-(1) and 5-bromo-2-fluorobenzaldehyde were treated in a manner similar to Reference Example 7 to give the target compound. APCI-Mass m/Z 365/367 (M+H).

Workup

  1. customto give the target compound

Sources & evidence

ORD record
ord-49bd0998a9ff4aba89ebea992a3a3fdb
Source dataset
uspto-grants-2012_06
Patent number
US08202984B2

Reaction notes

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