5-Bromo-2-fluorobenzaldehyde → HCID 66608463, compound

HRID 221095Notes

Reaction equation

HRID 221095 reaction equation
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([C:10]2[S:11][CH:12]=[CH:13][CH:14]=2)[CH:7]=[CH:8][CH:9]=1)[CH3:2].[Br:15][C:16]1[CH:17]=[CH:18][C:19]([F:24])=[C:20]([CH:23]=1)[CH:21]=O>>[Br:15][C:16]1[CH:17]=[CH:18][C:19]([F:24])=[C:20]([CH2:21][C:12]2[S:11][C:10]([C:6]3[CH:7]=[CH:8][CH:9]=[C:4]([O:3][CH2:1][CH3:2])[CH:5]=3)=[CH:14][CH:13]=2)[CH:23]=1

Participants

3

Reactant 2

HCID 7363275-Bromo-2-fluorobenzaldehydeHCID 66608066HCID 66608066, compound

Product 1

HCID 66608463HCID 66608463, compound

Procedure

2-(3-Ethoxyphenyl)thiophene obtained in Reference Example 69-(1) and 5-bromo-2-fluorobenzaldehyde were treated in a manner similar to Reference Example 9 to give the target compound. APCI-Mass m/Z 391/393 (M+H).

Workup

  1. customto give the target compound

Sources & evidence

ORD record
ord-4c7cb50a22c24a2e92affecca9035fef
Source dataset
uspto-grants-2012_06
Patent number
US08202984B2

Reaction notes

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