5-Bromo-2-fluorobenzaldehyde → HCID 66608370, compound

HRID 221096Notes

Reaction equation

HRID 221096 reaction equation
[F:1][C:2]1[CH:3]=[C:4]([C:8]2[S:9][CH:10]=[CH:11][CH:12]=2)[CH:5]=[CH:6][CH:7]=1.[Br:13][C:14]1[CH:15]=[CH:16][C:17]([F:22])=[C:18]([CH:21]=1)[CH:19]=O>>[Br:13][C:14]1[CH:15]=[CH:16][C:17]([F:22])=[C:18]([CH2:19][C:10]2[S:9][C:8]([C:4]3[CH:5]=[CH:6][CH:7]=[C:2]([F:1])[CH:3]=3)=[CH:12][CH:11]=2)[CH:21]=1

Participants

3

Reactant 2

HCID 7363275-Bromo-2-fluorobenzaldehydeHCID 22486407HCID 22486407, compound

Product 1

HCID 66608370HCID 66608370, compound

Procedure

2-(3-Fluorophenyl)thiophene obtained in Reference Example 75-(1) and 5-bromo-2-fluorobenzaldehyde were treated in a manner similar to Reference Example 7 to give the target compound.

Workup

  1. customto give the target compound

Sources & evidence

ORD record
ord-a8bb7dbd26604919a3e058ce6726a9cb
Source dataset
uspto-grants-2012_06
Patent number
US08202984B2

Reaction notes

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