5-Bromo-2-methylbenzoic acid → HCID 66608400, compound

HRID 221100Notes

Reaction equation

HRID 221100 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[S:9][CH:10]=[CH:11][CH:12]=2)[CH:5]=[CH:6][CH:7]=1.[Br:13][C:14]1[CH:15]=[CH:16][C:17]([CH3:23])=[C:18]([CH:22]=1)[C:19](O)=O>>[Br:13][C:14]1[CH:15]=[CH:16][C:17]([CH3:23])=[C:18]([CH2:19][C:10]2[S:9][C:8]([C:4]3[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=3)=[CH:12][CH:11]=2)[CH:22]=1

Participants

3

Reactant 2

HCID 3460045-Bromo-2-methylbenzoic acidHCID 123624442-(3-Chlorophenyl)thiophene

Product 1

HCID 66608400HCID 66608400, compound

Procedure

2-(3-Chlorophenyl)thiophene obtained in Reference Example 85-(1) and 5-bromo-2-methylbenzoic acid obtained in Reference Example 4-(1) were treated in a manner similar to Reference Example 5 to give the target compound as colorless oil.

Workup

  1. addition4-(1) were treated in a manner similar to Reference Example 5

Sources & evidence

ORD record
ord-d294767297444f3083076ed6ebd9bc6e
Source dataset
uspto-grants-2012_06
Patent number
US08202984B2

Reaction notes

Loading…