(3-Bromopropyl)benzene → HCID 21781259, compound

HRID 2211000Notes

Reaction equation

HRID 2211000 reaction equation
[CH3:1][C:2]1[CH2:3][C:4](=[O:15])[N:5]([CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[N:6]=1.[CH3:16]C1NNC(=O)C=1.BrCCCC1C=CC=CC=1>>[CH3:1][C:2]1[CH2:3][C:4](=[O:15])[N:5]([CH2:7][CH2:8][CH2:9][C:10]2[CH:16]=[CH:14][CH:13]=[CH:12][CH:11]=2)[N:6]=1

Participants

4

Reactant 3

HCID 12503(3-Bromopropyl)benzeneHCID 3197713H-Pyrazol-3-one, 2,4-dihydro-5-methyl-HCID 3715235HCID 3715235, compound

Product 1

HCID 21781259HCID 21781259, compoundYield 69%

Procedure

By a procedure similar to that for 2,4-dihydro-5-methyl-2-octyl-3H-pyrazol-3-one, starting from 3-methyl-3-pyrazoline-5-one (19.63 g, 0.20 mol) and 1-bromo-3-phenylpropane (39.80 g, 0.20 mol), 2,4-dihydro-5-methyl-2-(3-phenylpropyl)-3H-pyrazol-3-one (29.40 g, 69%) was obtained as colorless needles, m.p. 103°-105° C.

Sources & evidence

ORD record
ord-e3a43a9f2c2848e491e915da0987a563
Source dataset
uspto-grants-1995_10
Patent number
US05461155

Reaction notes

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