Benzothiazole → 1-(Benzothiazol-2-ylmethyl)-5-bromo-2-chlorobenzene

HRID 221107Notes

Reaction equation

HRID 221107 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.[Br:10][C:11]1[CH:12]=[CH:13][C:14]([Cl:19])=[C:15]([CH:18]=1)[CH:16]=O>>[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[CH2:16][C:15]1[CH:18]=[C:11]([Br:10])[CH:12]=[CH:13][C:14]=1[Cl:19]

Participants

3

Reactant 2

HCID 7222BenzothiazoleHCID 106089255-Bromo-2-chlorobenzaldehyde

Product 1

HCID 666082831-(Benzothiazol-2-ylmethyl)-5-bromo-2-chlorobenzene

Procedure

Benzothiazole and 5-bromo-2-chlorobenzaldehyde obtained in Reference Example 16-(1) were treated in a manner similar to Reference Example 100 to give the target compound. APCI-Mass m/Z 338/340 (M+H).

Workup

  1. additionwere treated in a manner similar to Reference Example 100
  2. customto give the target compound

Sources & evidence

ORD record
ord-d1c0b6d97a0d4145818ce7e83c32d5a8
Source dataset
uspto-grants-2012_06
Patent number
US08202984B2

Reaction notes

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