Triethylamine → HCID 86749079, compound

Participants

Reaction Steps

In 100 ml of ethanol was dissolved 11.85 g of 3,3-dimethyl-1-[1-(R)-phenylethyl]-pyrrolidine-2,4-dione. To the solution were added 8 g of hydroxylamine hydrochloride and 45 ml of triethylamine, followed by refluxing for 1 hour. The solvent was removed under reduced pressure, and to the residue was added 300 ml of chloroform. The chloroform solution was washed successively with a 10% citric acid aqueous solution and water and dried over anhydrous sodium sulfate. The solvent was removed under reduced pressure to yield 11.5 g of the titled compound.

Provenance & Evidence