2-Bromothiophene → 2-(4-Methylphenyl)thiophene

HRID 221122Notes

Reaction equation

HRID 221122 reaction equation
Br[C:2]1[S:3][CH:4]=[CH:5][CH:6]=1.[CH3:7][C:8]1[CH:13]=[CH:12][C:11](B(O)O)=[CH:10][CH:9]=1>>[CH3:7][C:8]1[CH:13]=[CH:12][C:11]([C:2]2[S:3][CH:4]=[CH:5][CH:6]=2)=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 138512-BromothiopheneHCID 79799Tolylboronic acid

Product 1

HCID 41284662-(4-Methylphenyl)thiophene

Procedure

2-Bromothiophene and 4-methylphenylboronic acid were treated in a manner similar to Reference Example 20-(1) to give the target compound.

Workup

  1. customto give the target compound

Sources & evidence

ORD record
ord-b098da57e4ce48ba94078ac9254dc7ea
Source dataset
uspto-grants-2012_06
Patent number
US08202984B2

Reaction notes

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