反应详情

温度

50 °C

A mixture of N-(3-(trifluoromethyl)phenyl)-N-(2-chloro-2-propenyl)cyanamide (168.67 g), methyl isobutyl ketone (674.70 g) and ammonium sulfide solution, yellow (518.77 g) having an S content of 6% was stirred at 50° C. for 9 hours. After cooling to 20° C., water (1774.70 g) was poured into the reaction mixture, which was then shaken and fractionated with a separatory funnel. The water layer was extracted twice with methyl isobutyl ketone (53.72 g×2). The combined methyl isobutyl ketone layer was washed with water (81.05 g) to give a methyl isobutyl ketone solution (938.58 g) of N-(3-(trifluoromethyl)phenyl)-N-(2-chloro-2-propenyl)thiourea.

1. temperatureAfter cooling to 20° C.
2. stirringwas then shaken
3. customfractionated with a separatory funnel
4. extractionThe water layer was extracted twice with methyl isobutyl ketone (53.72 g×2)
5. washThe combined methyl isobutyl ketone layer was washed with water (81.05 g)