HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2211287Generated: October 26, 2026
Water → Methyl 2,3-dihydro-4-methyl-2-thioxothieno[3,4-d]imidazole-6-carboxylate
https://huagongshe.com/reaction/2211287
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 1,1'-Thiocarbonyldiimidazole | HCID 80264 | — |
| Reactant | Methyl 3,4-diamino-5-methylthiophene-2-carboxylate | HCID 18693138 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Methyl 2,3-dihydro-4-methyl-2-thioxothieno[3,4-d]imidazole-6-carboxylate | HCID 19376767 | — |
Reaction Steps
A mixture of methyl 3,4-diamino-2-methylthiophene-5-carboxylate (1.0 g) and N,N'-thiocarbonyldiimidazole (1.1 g) in DMF (5 ml) was stirred at 50° C. for one hour. To the reaction mixture was added water to give crystals. Recrystallization from DMF-water afforded colorless prisms (1.2 g, quantitatively), m.p. 285°-288° C. (dec.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US05463073 |
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| Source dataset | uspto-grants-1995_10 |
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| ORD ID | ord-6367b16a79fe4ff8a330aff245e33d58 |
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| Source note | uspto-grants-1995_10 |
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