HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Tetralone → Naphthalene, 1,2-dihydro-3-methoxy-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Tetralone | HCID 68266 | — |
| Reactant | p-Toluenesulfonic acid monohydrate | HCID 521998 | — |
| Reactant | Methylorthoformate | HCID 53629101 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | Naphthalene, 1,2-dihydro-3-methoxy- | HCID 11105653 | 75% |
Reaction Steps
A mixture of 1.4 g of 2-tetralone, 1.5 mL of methyl orthoformate, and a few crystals of para-toluenesulfonic acid monohydrate in 75 mL of benzene was stirred for 22 hours and then evaporated in vacuo. The residue was chromatographed on Florisil® eluting with hexane/ethyl ether to provide 1.15 g (75%) of the desired title intermediate. NMR.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05462954 |
| Source dataset | uspto-grants-1995_10 |
| ORD ID | ord-e82e2fce827e40b7ad8e30cea3f679d0 |
| Source note | uspto-grants-1995_10 |