5-Bromo-2-chlorobenzaldehyde → HCID 66608064, compound

HRID 221149Notes

Reaction equation

HRID 221149 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[N:6]1[CH:10]=[CH:9][CH:8]=[N:7]1.[Br:11][C:12]1[CH:13]=[CH:14][C:15]([Cl:20])=[C:16]([CH:19]=1)[CH:17]=O>>[Br:11][C:12]1[CH:13]=[CH:14][C:15]([Cl:20])=[C:16]([CH2:17][C:5]2[S:1][C:2]([N:6]3[CH:10]=[CH:9][CH:8]=[N:7]3)=[CH:3][CH:4]=2)[CH:19]=1

Participants

3

Reactant 2

HCID 106089255-Bromo-2-chlorobenzaldehydeHCID 125544841-(Thiophen-2-yl)-1H-pyrazole

Product 1

HCID 66608064HCID 66608064, compound

Procedure

1-(2-thienyl)pyrazole (see: Chemica Scripta (1979) 13, 157-161) and 5-bromo-2-chlorobenzaldehyde obtained in Reference Example 16-(1) were used and treated in a manner similar to Reference Example 7 to give the title compound as colorless solid. APCI-Mass m/z 353/355 (M+H).

Workup

  1. additiontreated in a manner similar to Reference Example 7

Sources & evidence

ORD record
ord-86b45f36947d41c7a2af24d7ce580290
Source dataset
uspto-grants-2012_06
Patent number
US08202984B2

Reaction notes

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