HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methoxy-1,3-dihydro-2-benzofuran-1,3-dione → HCID 15378693, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methoxy-1,3-dihydro-2-benzofuran-1,3-dione | HCID 639748 | — |
| Reactant | 2-(4-(6-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethan-1-amine | HCID 14699857 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 15378693 | HCID 15378693 | — |
Reaction Steps
A stirred mixture of 2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethylamine (2.63 g. 0.01 mole) and 4-methoxyphthalic anhydride (1.78 g. 0.01 mole) in dichloromethane (100 ml) is stirred at room temperature for 3 hours. The solvent is then removed under reduced pressure and the residual material is purified by flash chromatography. The product is purified further by recrystallization to give N-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-4-methoxyphthalimide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE039265E1 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-783edcfb1c41471c8762b68e8c2b05f4 |
| Source note | uspto-grants-2006_09 |