2-Ethylhexylamine → HCID 21960556, compound

Participants

Reaction Steps

12 g (60.3 mmol) of 2,3-dichloroquinoxaline are dissolved in 125 ml of THF with 9.5 g (72.1 mmol) of diisopropylethylamine. 8.5 g (66 mmol) of 2-ethylhexylamine are added dropwise to the solution, and the reaction is refluxed for a total of 48 hours until starting material is no longer visible according to TLC (silica gel: n-heptane/MTB ether). The reaction solution is evaporated to dryness in a rotary evaporator, and the crude product is chromatographed over silica gel using n-heptane/MTB ether. The product-containing fractions are collected and evaporated in a rotary evaporator. Yield: 11.8 g (67%)

Provenance & Evidence