Water → HCID 21960827, compound

Participants

Reaction Steps

Next, 91 g (0.31 mol) of the 1,2-di(n-hexyloxy)-4-methylbenzene was dissolved in 270 g of dichloromethane. While cooling in an ice/water bath, 49.7 g (0.31 mol) of bromine was added dropwise at a temperature below 10° C. After the completion of dropwise addition, 200 g of water was added. The organic layer was separated and washed with a saturated sodium hydrogen carbonate aqueous solution. The organic layer was concentrated on a rotary evaporator, yielding 120 g of an oily matter. This was distilled in vacuum (boiling point 180–190° C./0.5 Torr), obtaining 104 g (yield 90%) of 5-bromo-1,2-di(n-hexyloxy)-4-methylbenzene.

Provenance & Evidence