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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2211611Generated: November 1, 2026

3-(3-(Piperidin-1-yl)propyl)-5-(trifluoromethyl)benzenamine → 3-(1-Methylpiperidin-4-yl)-5-(trifluoromethyl)aniline

https://huagongshe.com/reaction/2211611

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(3-(Piperidin-1-yl)propyl)-5-(trifluoromethyl)benzenamineHCID 21959527—
ReactantN-[3-(1-Methylpiperidin-4-yl)-5-trifluoromethyl-phenyl]-acetamideHCID 21959571—
Product3-(1-Methylpiperidin-4-yl)-5-(trifluoromethyl)anilineHCID 21959379—

Reaction Steps

3-(1-Methylpiperidin-4-yl)-5-trifluoromethyl-phenylamine was prepared from N-[3-(1-methylpiperidin-4-yl)-5-trifluoromethyl-phenyl]-acetamide similar to the procedure described in the preparation of 3-(3-piperidin-1-yl-propyl)-5-trifluoromethyl-phenylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07101868B2
Source datasetuspto-grants-2006_09
ORD IDord-abd083433e5b41d3b46e7e68e37597d3
Source noteuspto-grants-2006_09