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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2211621Generated: October 30, 2026

1-(2-Chloroethyl)piperidine → 1-[2-(5-Nitro-2-pentafluoroethyl-phenoxy)-ethyl]-piperidine

https://huagongshe.com/reaction/2211621

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Chloroethyl)piperidineHCID 74827—
ReactantPhenol, 5-nitro-2-(1,1,2,2,2-pentafluoroethyl)-HCID 17756181—
Reactant1-[2-(2-Tert-butyl-5-nitro-phenoxy)-ethyl]-piperidineHCID 21959506—
Product1-[2-(5-Nitro-2-pentafluoroethyl-phenoxy)-ethyl]-piperidineHCID 21959346—

Reaction Steps

1-[2-(5-Nitro-2-pentafluoroethyl-phenoxy)-ethyl]-piperidine was prepared from 5-nitro-2-pentafluoroethylphenol and 1-(2-chloroethyl)piperidine by a procedure similar to that described in the preparation of 1-[2-(2-tert-butyl-5-nitro-phenoxy)-ethyl]-piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07101868B2
Source datasetuspto-grants-2006_09
ORD IDord-2c62e43bed6a46d3861d02310830eb20
Source noteuspto-grants-2006_09