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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2211767Generated: October 31, 2026

4-Fluorobenzoyl chloride → 4-Fluoro-N-[3-(4-isopropylphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl]benzamide

https://huagongshe.com/reaction/2211767

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzoyl chlorideHCID 67879—
Reactant3-(4-Isopropylphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-amineHCID 10519978—
Product4-Fluoro-N-[3-(4-isopropylphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-yl]benzamideHCID 2196131665%

Reaction Steps

By using 3-(4-isopropylphenyl)-2,2,4,6,7-pentamethyl-2,3-dihydro-1-benzofuran-5-amine and 4-fluorobenzoyl chloride, the title compound was synthesized according to Example 1b. Yield: 65%. Amorphous.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07101867B2
Source datasetuspto-grants-2006_09
ORD IDord-0ade595772754c82b3a2aa8775190859
Source noteuspto-grants-2006_09