HCID 21962567, compound → HCID 21962574, compound

HRID 2211811Notes

Reaction equation

HRID 2211811 reaction equation
[O:1]=[C:2]1[N:7](CC2C=CC(OC)=CC=2)[C:6]2[CH:17]=[CH:18][C:19]([CH2:21][CH:22]([C:29]3[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=3)[CH2:23][C:24]([O:26][CH2:27][CH3:28])=[O:25])=[CH:20][C:5]=2[O:4][CH2:3]1>C(O)C.[Pd]>[O:1]=[C:2]1[NH:7][C:6]2[CH:17]=[CH:18][C:19]([CH2:21][CH:22]([C:29]3[CH:30]=[CH:31][CH:32]=[CH:33][CH:34]=3)[CH2:23][C:24]([O:26][CH2:27][CH3:28])=[O:25])=[CH:20][C:5]=2[O:4][CH2:3]1

Participants

4

Reactant 1

HCID 21962567HCID 21962567, compound

Product 1

HCID 21962574HCID 21962574, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

To a solution of ethyl 4-[3-oxo-4-[p-methoxybenzyl]-3,4-dihydro-2H-1,4-benzoxazin-7-yl]-3-phenylbutanoate in ethanol is added 10% Pd/C and the compound hydrogenated in a Parr apparatus. Evaporation of the solvent yields the title compound.

Workup

  1. customEvaporation of the solvent

Sources & evidence

ORD record
ord-3043b4f58fbe4b79bb5cd8465f409128
Source dataset
uspto-grants-2006_09
Patent number
US07101876B2

Reaction notes

Loading…