Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2211841Generated: October 26, 2026

1-(Bromomethyl)-4-(trifluoromethoxy)benzene → tert-Butyl 4-[(Benzyloxy)methyl]hexahydro-3-oxo-2-[4-(trifluoromethoxy)benzyl]-1H-1,4-diazepine-1-carboxylate

https://huagongshe.com/reaction/2211841

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Bromomethyl)-4-(trifluoromethoxy)benzeneHCID 142785—
Reactanttert-Butyl 4-[(Benzyloxy)methyl]hexahydro-3-oxo-1H-1,4-diazepine-1-carboxylateHCID 21962085—
Producttert-Butyl 4-[(Benzyloxy)methyl]hexahydro-3-oxo-2-[4-(trifluoromethoxy)benzyl]-1H-1,4-diazepine-1-carboxylateHCID 21962099—

Reaction Steps

The title compound was prepared from tert-butyl 4-[(benzyloxy)methyl]hexahydro-3-oxo-1H-1,4-diazepine-1-carboxylate and 4-(trifluoromethoxy)benzylbromide essentially following the procedure described in Example 3, Step 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07101871B2
Source datasetuspto-grants-2006_09
ORD IDord-a85f5c8895684f5aaeec6439fc6ef137
Source noteuspto-grants-2006_09