HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(2-Nitrophenyl)ethyl p-toluenesulfonate → HCID 21963194, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(2-Nitrophenyl)ethyl p-toluenesulfonate | HCID 562663 | — |
| Reactant | 3-(1-Piperazinyl)-1,2-benzisothiazole monohydrochloride | HCID 11521711 | — |
| Product | HCID 21963194 | HCID 21963194 | 75% |
Reaction Steps
3-{4-[2-(2-Nitro-phenyl)-ethyl]-piperazin-1-yl}-1,2-benzisothiazole was prepared according to the general method as outlined in Preparation 2 starting with 3-piperazin-1-yl-benzoisothiazole hydrochloride (13.37 g, 52.4 mmol) and 2-nitrophenethyl tosylate (15.3 g, 47.7 mmol). The product was isolated via column chromatography to afford 13.08 g of a viscous, brown liquid. Yield 75%; MS (APCI): 369 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101886B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-bbce4f40a2e64a008c3676f43661dfe6 |
| Source note | uspto-grants-2006_09 |