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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2211918Generated: October 25, 2026

N-[4-(2-Chloroethyl)-2,5-dimethylphenyl]acetamide → N-(4-{2-[4-(1H-Indazol-3-YL)-piperazin-1-YL]-ethyl}-2.5-dimethyl-phenyl)-acetamide

https://huagongshe.com/reaction/2211918

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-[4-(2-Chloroethyl)-2,5-dimethylphenyl]acetamideHCID 21963433—
Reactant3-(Piperazin-1-yl)-1H-indazole hydrochlorideHCID 21963434—
ProductN-(4-{2-[4-(1H-Indazol-3-YL)-piperazin-1-YL]-ethyl}-2.5-dimethyl-phenyl)-acetamideHCID 21963196—

Reaction Steps

N-[4-(2-Chloro-ethyl)-2,5-dimethyl-phenyl]-acetamide (0.142 g, 0.631 mmol) was reacted with 3-piperazin-1-yl-1H-indazole hydrochloride (0.226 g, 0.946 mmol) according to the method outlined in Example 501.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07101886B2
Source datasetuspto-grants-2006_09
ORD IDord-cf021d051ce44bdc8dbf5e0733046c52
Source noteuspto-grants-2006_09