[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamine → HCID 21962923, compound

HRID 2211990Notes

Reaction equation

HRID 2211990 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=1[Cl:17])[CH2:5][N:6]1[CH2:11][CH2:10][O:9][CH:8]([CH2:12][NH2:13])[CH2:7]1.[NH2:18][C:19]([C:21]1[CH:26]=[CH:25][C:24]([CH2:27][C:28](O)=[O:29])=[CH:23][CH:22]=1)=[O:20]>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=1[Cl:17])[CH2:5][N:6]1[CH2:11][CH2:10][O:9][CH:8]([CH2:12][NH:13][C:28](=[O:29])[CH2:27][C:24]2[CH:25]=[CH:26][C:21]([C:19]([NH2:18])=[O:20])=[CH:22][CH:23]=2)[CH2:7]1

Participants

3

Reactant 2

HCID 10308229[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamineHCID 141809504-(Aminocarbonyl)benzeneacetic acid

Product 1

HCID 21962923HCID 21962923, compoundYield 11.5%

Procedure

Example 10 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 1 (0.055 g) and [4-(aminocarbonyl)phenyl]acetic acid (0.036 g) to give the title compound (0.01 g).

Workup

  1. customExample 10 was prepared in an analogous manner to Example 1 using

Sources & evidence

ORD record
ord-636e5d3c267041cc8bab90d5a0ac8f79
Source dataset
uspto-grants-2006_09
Patent number
US07101882B2

Reaction notes

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