2,4-Dichlorophenylacetic acid → HCID 21962998, compound

HRID 2211997Notes

Reaction equation

HRID 2211997 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=1[Cl:17])[CH2:5][N:6]1[CH2:11][CH2:10][O:9][CH:8]([CH2:12][NH2:13])[CH2:7]1.[Cl:18][C:19]1[CH:24]=[C:23]([Cl:25])[CH:22]=[CH:21][C:20]=1[CH2:26][C:27](O)=[O:28]>>[Cl:1][C:2]1[CH:3]=[C:4]([CH:14]=[CH:15][C:16]=1[Cl:17])[CH2:5][N:6]1[CH2:11][CH2:10][O:9][CH:8]([CH2:12][NH:13][C:27](=[O:28])[CH2:26][C:20]2[CH:21]=[CH:22][C:23]([Cl:25])=[CH:24][C:19]=2[Cl:18])[CH2:7]1

Participants

3

Reactant 2

HCID 882092,4-Dichlorophenylacetic acidHCID 10308229[4-(3,4-Dichlorobenzyl)morpholin-2-yl]methylamine

Product 1

HCID 21962998HCID 21962998, compound

Procedure

Example 18 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 1 (0.055 g) and (2,4-dichlorophenyl)acetic acid (0.0.41 g) to give the title compound (0.019 g).

Workup

  1. customExample 18 was prepared in an analogous manner to Example 1 using

Sources & evidence

ORD record
ord-57fae87a1aa247b7996f69ee4ccf6f88
Source dataset
uspto-grants-2006_09
Patent number
US07101882B2

Reaction notes

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