HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Mesylphenylacetic acid → N-{[(2R)-4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-2-[4-(methylsulfonyl)phenyl]acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Mesylphenylacetic acid | HCID 572345 | — |
| Reactant | 1-[(2R)-4-(3,4-Dichlorobenzyl)morpholin-2-yl]methanamine | HCID 11346392 | — |
| Product | N-{[(2R)-4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-2-[4-(methylsulfonyl)phenyl]acetamide | HCID 68882709 | 48.8% |
Reaction Steps
Example 40 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 10 (0.055 g) and 4-(methylsulphonyl)phenylacetic acid (0.050 g) to give the title compound (0.046 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101882B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-a28ecd88c9e84b9fa43428d2b9887acf |
| Source note | uspto-grants-2006_09 |