HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-2-phenyl-4-oxazoleacetic acid → N-{[(2S)-4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-2-phenyl-4-oxazoleacetic acid | HCID 2775139 | — |
| Reactant | (S)-(4-(3,4-Dichlorobenzyl)morpholin-2-YL)methanamine | HCID 10171585 | — |
| Product | N-{[(2S)-4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)acetamide | HCID 68882787 | 48.5% |
Reaction Steps
Example 54 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 9 (0.055 g) and 2-phenyl-5-methyl-4-oxazolylacetic acid (0.050 g) to give the title compound (0.046 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101882B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-0b4539cd12d4491e89b7423a2514a81f |
| Source note | uspto-grants-2006_09 |