HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Methyl-2-phenyl-4-oxazoleacetic acid → N-{[(2R)-4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-2-(5-methyl-2-phenyl-1,3-oxazolyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Methyl-2-phenyl-4-oxazoleacetic acid | HCID 2775139 | — |
| Reactant | 1-[(2R)-4-(3,4-Dichlorobenzyl)morpholin-2-yl]methanamine | HCID 11346392 | — |
| Product | N-{[(2R)-4-(3,4-Dichlorobenzyl)morpholin-2-yl]methyl}-2-(5-methyl-2-phenyl-1,3-oxazolyl)acetamide | HCID 9891043 | 44.3% |
Reaction Steps
Example 55 was prepared in an analogous manner to Example 1 using a mixture of Intermediate 10 (0.055 g) and 2-phenyl-5-methyl-4-oxazolylacetic acid (0.050 g) to give the title compound (0.042 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101882B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-e76c8dade4df43afbddcdf75b336bc18 |
| Source note | uspto-grants-2006_09 |