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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2212034Generated: November 1, 2026

(2E)-3-(4-((Methylsulfonyl)oxy)phenyl)-2-propenoic acid → (E)-3-(4-(trifluoromethylsulfonyloxy)phenyl)acrylic acid

https://huagongshe.com/reaction/2212034

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2E)-3-(4-((Methylsulfonyl)oxy)phenyl)-2-propenoic acidHCID 15726601—
ReactantTrifluoromethansulfonic acid anhydride methanesulfonyl chlorideHCID 86589944—
Product(E)-3-(4-(trifluoromethylsulfonyloxy)phenyl)acrylic acidHCID 21964125—

Reaction Steps

13.4 g of (E)-3-(4-(trifluoromethylsulfonyloxy)phenyl)acrylic acid was synthesized as described for (E)-3-(4-(methanesulfonyloxy)phenyl)acrylic acid using trifluoromethansulfonic acid anhydride methanesulfonyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07101898B2
Source datasetuspto-grants-2006_09
ORD IDord-d9d34d4d76dc4bf28262886936d523c5
Source noteuspto-grants-2006_09