HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-1-(pyrrolidin-2-ylmethyl)piperidine → 3-[(E)-3-Oxo-3-((S)-2-((piperidin-1-yl)methyl)pyrrolidin-1-yl)propenyl]benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-1-(pyrrolidin-2-ylmethyl)piperidine | HCID 7022796 | — |
| Reactant | 3-Cyanocinnamic acid | HCID 13370798 | — |
| Product | 3-[(E)-3-Oxo-3-((S)-2-((piperidin-1-yl)methyl)pyrrolidin-1-yl)propenyl]benzonitrile | HCID 58697196 | — |
Reaction Steps
370 mg of the title compound were synthesized as described for (E)-3-(4-bromophenyl)-1-((S)-2-((pyrrolidin-1-yl)methyl)pyrrolidin-1-yl)propenone, using (E)-3-(3-cyanophenyl)acrylic acid instead of (E)-4-bromocinnamic acid and 1-(((S)-pyrrolidin-2-yl)methyl)piperidine instead of (S)-2-((pyrrolidin-1-yl)methyl)pyrrolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101898B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-a30934d21614406c861d576f3395b67e |
| Source note | uspto-grants-2006_09 |