HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-1-(pyrrolidin-2-ylmethyl)piperidine → Methanesulfonic Acid 4-[(E)-3-oxo-3-((S)-2-((piperidin-1-yl)methyl)pyrrolidin-1-yl)propenyl]phenyl Ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-1-(pyrrolidin-2-ylmethyl)piperidine | HCID 7022796 | — |
| Reactant | (2E)-3-(4-((Methylsulfonyl)oxy)phenyl)-2-propenoic acid | HCID 15726601 | — |
| Product | Methanesulfonic Acid 4-[(E)-3-oxo-3-((S)-2-((piperidin-1-yl)methyl)pyrrolidin-1-yl)propenyl]phenyl Ester | HCID 58697214 | — |
Reaction Steps
230 mg of the title compound were synthesized as described for (E)-3-(4-bromophenyl)-1-((S)-2-((pyrrolidin-1-yl)methyl)pyrrolidin-1-yl)propenone, using (E)-3-(4-(methanesulfonyloxy)phenyl)acrylic acid instead of (E)-4-bromocinnamic acid and 1-(((S)-pyrrolidin-2-yl)methyl)piperidine instead of (S)-2-((pyrrolidin-1-yl)methyl)pyrrolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101898B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-535fe921972c4b2585b0ed4e1f33fa4e |
| Source note | uspto-grants-2006_09 |