p-(Trifluoromethoxy)phenol → 5-(Trifluoromethoxy)benzofuran-2-carboxylic acid

HRID 2212049Notes

Reaction equation

HRID 2212049 reaction equation
FC(F)(F)[C:3]1[CH:4]=[CH:5][C:6]2[O:10][C:9]([C:11]([OH:13])=[O:12])=[CH:8][C:7]=2[CH:14]=1.[F:17][C:18]([F:28])([F:27])[O:19]C1C=CC(O)=CC=1>>[F:17][C:18]([F:28])([F:27])[O:19][C:3]1[CH:4]=[CH:5][C:6]2[O:10][C:9]([C:11]([OH:13])=[O:12])=[CH:8][C:7]=2[CH:14]=1

Participants

3

Reactant 2

HCID 70015p-(Trifluoromethoxy)phenolHCID 102361385-(trifluoromethyl)benzofuran-2-carboxylic Acid

Product 1

HCID 219641505-(Trifluoromethoxy)benzofuran-2-carboxylic acid

Procedure

93 mg of 5-(trifluoromethoxy)benzofuran-2-carboxylic acid were prepared as described for 5-(trifluoromethyl)benzofuran-2-carboxylic acid, using 4-(trifluoromethoxy)phenol instead of 4-(trifluoromethyl)phenol.

Sources & evidence

ORD record
ord-2fda8c0b26964553af704a26cdf3c959
Source dataset
uspto-grants-2006_09
Patent number
US07101898B2

Reaction notes

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