3-(Trifluoromethyl)phenol → 6-(Trifluoromethyl)benzofuran-2-carboxylic acid

HRID 2212050Notes

Reaction equation

HRID 2212050 reaction equation
FC(F)(F)[C:3]1[CH:4]=[CH:5][C:6]2[O:10][C:9]([C:11]([OH:13])=[O:12])=[CH:8][C:7]=2[CH:14]=1.[F:17][C:18]([F:27])([F:26])C1C=C(O)C=CC=1>>[F:17][C:18]([F:27])([F:26])[C:4]1[CH:3]=[CH:14][C:7]2[CH:8]=[C:9]([C:11]([OH:13])=[O:12])[O:10][C:6]=2[CH:5]=1

Participants

3

Reactant 2

HCID 73763-(Trifluoromethyl)phenolHCID 102361385-(trifluoromethyl)benzofuran-2-carboxylic Acid

Product 1

HCID 219641426-(Trifluoromethyl)benzofuran-2-carboxylic acid

Procedure

93 mg of 6-(trifluoromethyl)benzofuran-2-carboxylic acid were prepared as described for 5-(trifluoromethyl)benzofuran-2-carboxylic acid, using 3-(trifluoromethyl)phenol instead of 4-(trifluoromethyl)phenol.

Sources & evidence

ORD record
ord-9d85f15399c94e4f9cc07e74bb4d1932
Source dataset
uspto-grants-2006_09
Patent number
US07101898B2

Reaction notes

Loading…