HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-1-(pyrrolidin-2-ylmethyl)piperidine → (S)-(2-(piperidin-1-ylmethyl)pyrrolidin-1-yl)(6-(trifluoromethyl)benzofuran-2-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-1-(pyrrolidin-2-ylmethyl)piperidine | HCID 7022796 | — |
| Reactant | 6-(Trifluoromethyl)benzofuran-2-carboxylic acid | HCID 21964142 | — |
| Product | (S)-(2-(piperidin-1-ylmethyl)pyrrolidin-1-yl)(6-(trifluoromethyl)benzofuran-2-yl)methanone | HCID 44411624 | — |
Reaction Steps
71 mg of the title compound were synthesized as described for (E)-3-(4-bromophenyl)-1-((S)-2-((pyrrolidin-1-yl)methyl)pyrrolidin-1-yl)propenone, using 6-(trifluoromethyl)benzofuran-2-carboxylic acid instead of (E)-4-bromocinnamic acid and 1-(((S)-pyrrolidin-2-yl)methyl)piperidine instead of (S)-2-((pyrrolidin-1-yl)methyl)pyrrolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101898B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-0c764bd5f91645b9bacdee365f8c44f6 |
| Source note | uspto-grants-2006_09 |