HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-N-Ethyl-N-(pyrrolidin-2-ylmethyl)ethanamine → ((S)-2-(Diethylaminomethyl)pyrrolidin-1-yl)-(5-(trifluoromethyl)benzofuran-2-yl)methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-N-Ethyl-N-(pyrrolidin-2-ylmethyl)ethanamine | HCID 7141622 | — |
| Reactant | 5-(trifluoromethyl)benzofuran-2-carboxylic Acid | HCID 10236138 | — |
| Product | ((S)-2-(Diethylaminomethyl)pyrrolidin-1-yl)-(5-(trifluoromethyl)benzofuran-2-yl)methanone | HCID 44411604 | — |
Reaction Steps
110 mg of the title compound were synthesized as described for (E)-3-(4-bromophenyl)-1-((S)-2-((pyrrolidin-1-yl)methyl)pyrrolidin-1-yl)propenone, using 5-(trifluoromethyl)benzofuran-2-carboxylic acid instead of (E)-4-bromocinnamic acid and N,N-diethyl-N-(((S)-pyrrolidin-2-yl)methyl)amine instead of (S)-2-((pyrrolidin-1-yl)methyl)pyrrolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101898B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-73f6ca62feb7404eb6820685c5d4a009 |
| Source note | uspto-grants-2006_09 |