HuagongsheHuagongshe Chemistry Print Report · For research reference only
(E)-3-(4-(Isobutyl)phenyl)but-2-enoic acid → (E)-3-(4-(Isobutyl)phenyl)-1-((S)-2-((piperidin-1-yl)methyl)pyrrolidin-1-yl)but-2-en-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (E)-3-(4-(Isobutyl)phenyl)but-2-enoic acid | HCID 6030310 | — |
| Reactant | (S)-1-(pyrrolidin-2-ylmethyl)piperidine | HCID 7022796 | — |
| Product | (E)-3-(4-(Isobutyl)phenyl)-1-((S)-2-((piperidin-1-yl)methyl)pyrrolidin-1-yl)but-2-en-1-one | HCID 58697232 | — |
Reaction Steps
130 mg of the title compound were synthesized as described for (E)-3-(4-bromophenyl)-1-((S)-2-((pyrrolidin-1-yl)methyl)pyrrolidin-1-yl)propenone, using (E)-3-(4-(Isobutyl)phenyl)but-2-enoic acid instead of (E)-4-bromocinnamic acid and 1-(((S)-pyrrolidin-2-yl)methyl)piperidine instead of (S)-2-((pyrrolidin-1-yl)methyl)pyrrolidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07101898B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-f46586d60c794973aa520798a775aaa8 |
| Source note | uspto-grants-2006_09 |