4-(Trifluoromethyl)piperidine → 1-(4-Benzenesulfonylbutyl)-4-trifluoromethylpiperidine

HRID 2212089Notes

Reaction equation

HRID 2212089 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][S:6]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)(=[O:8])=[O:7].[F:15][C:16]([F:24])([F:23])[CH:17]1[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1>>[C:9]1([S:6]([CH2:5][CH2:4][CH2:3][CH2:2][N:20]2[CH2:21][CH2:22][CH:17]([C:16]([F:24])([F:23])[F:15])[CH2:18][CH2:19]2)(=[O:8])=[O:7])[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 1364694-(Trifluoromethyl)piperidineHCID 114827894-Phenylsulfonylbutyl bromide

Product 1

HCID 696634961-(4-Benzenesulfonylbutyl)-4-trifluoromethylpiperidine

Procedure

Prepared from (4-bromobutane-1-sulfonyl)benzene and 4-trifluoromethylpiperidine by the method in Example 1.

Sources & evidence

ORD record
ord-d11c0e537cbd48a1a0e4634c3226eb9a
Source dataset
uspto-grants-2006_09
Patent number
US07101892B2

Reaction notes

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