1-Aminohomopiperidine → HCID 24758564, compound

HRID 221209Notes

Reaction equation

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[N:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[Cl:20])[N:11]=[C:10]([C:21](Cl)=[O:22])[CH2:9]2)=[CH:4][CH:3]=1.[N:24]1([NH2:31])[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>>[N:24]1([NH:31][C:21]([C:10]2[CH2:9][CH:8]([C:5]3[CH:4]=[CH:3][C:2]([Br:1])=[CH:7][CH:6]=3)[N:12]([C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][C:14]=3[Cl:20])[N:11]=2)=[O:22])[CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

Reactant 2

HCID 221981-Aminohomopiperidine

HCID 87324864HCID 87324864, compound

Product 1

HCID 24758564HCID 24758564, compound

Procedure

This compound was obtained following the same method described in Example 1 starting from 5-(4-bromophenyl)-1-(2,4-dichlorophenyl)-4,5-dihydro-pyrazole-3-carboxylic acid chloride and azepan-1-amine.

Workup

customThis compound was obtained

Sources & evidence

ORD record: ord-7b8c5bdcc60d4573a2797d96f08a9b2e
Source dataset: uspto-grants-2012_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08207156B2

Reaction notes

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