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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2212148Generated: October 31, 2026

4-(Trifluoromethoxy)phenylboronic acid → Ethyl 1-benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indole-2-carboxylate

https://huagongshe.com/reaction/2212148

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethoxy)phenylboronic acidHCID 2734386—
ReactantEthyl 1-benzyl-5-bromo-1H-indole-2-carboxylateHCID 21964289—
ProductEthyl 1-benzyl-5-[4-(trifluoromethoxy)phenyl]-1H-indole-2-carboxylateHCID 21964294—

Reaction Steps

The title compound was prepared from ethyl 5-bromo-1-benzyl-1H-indole-2-Carboxylate and 4-(trifluoromethoxy)phenylboronic acid in substantially the same manner, as described in step 2 of Example 1. The product was obtained as an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07101903B2
Source datasetuspto-grants-2006_09
ORD IDord-f01cdd36b49248af818011cff4ae3405
Source noteuspto-grants-2006_09