1,1'-Biphenyl-4-yl-boronic acid → HCID 10049054, compound

Participants

Reaction Steps

The title compound was prepared from [1-benzyl-5-bromo-2-(hydroxymethyl)-1H-indol-3-yl](oxo)acetic acid, potassium salt and 4-biphenylboronic acid in substantially the same manner, as described in step 4 of Example 9. The product was obtained as a white solid, mp: 254–255° C.; Mass spectrum (ESI, [M+H]+) m/z 444. 1H NMR (400 MHz, DMSO-d6) δ 8.26(s, 1H), 7.75–7.68 (m, 8H), 7.45–7.43 (m, 2H), 7.36–7.23 (m, 6H), 5.89 (s, 2H), 5.53 ppm (s, 2H).

Provenance & Evidence