Lithium hydroxide, monohydrate → HCID 21963704, compound

Participants

Reaction Steps

Add a solution of lithium hydroxide monohydrate (7 mg, 0.17 mmol) in water (2 mL) to a solution of [3-(9-chloro-3-methyl-4-oxo-5H-isoxazolo[4,3-c]quinolin-5-yl)-piperidin-1-yl]-acetic acid ethyl ester (45.7 mg, 0.11 mmol) in dioxane (3 mL). Stir the reaction at room temperature for 1 hour. Concentrate the reaction. Dissolve in chloroform and concentrate (×3) to assist in removal of solvents to yield the resulting 50.5 mg of the title compound as a white solid, quantitative yield. MS (ion spray) 376 (M+).

Provenance & Evidence