Iodomethyl pivalate → HCID 69584986, compound

HRID 2212437Notes

Reaction equation

C(OC[O:6][C:7](=[O:31])[C:8]([NH:29][NH2:30])([CH3:28])[CH2:9][C:10]1[CH:15]=[CH:14][C:13]([O:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])=[C:12]([O:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH:11]=1)(=O)C.[C:32]([O:38][CH2:39]I)(=[O:37])[C:33]([CH3:36])([CH3:35])[CH3:34]>>[CH3:34][C:33]([CH3:36])([CH3:35])[C:32]([O:38][CH2:39][O:31][C:7](=[O:6])[C:8]([NH:29][NH2:30])([CH3:28])[CH2:9][C:10]1[CH:15]=[CH:14][C:13]([O:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])=[C:12]([O:22][C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH:11]=1)=[O:37]

Participants

Reactant 2

HCID 104401Iodomethyl pivalate

HCID 69585130HCID 69585130, compound

Product 1

HCID 69584986HCID 69584986, compound

Procedure

Following the procedure for preparation of compound 101, and substituting bromomethyl acetate with iodomethyl pivalate, provided the title compound. 1H NMR (CD3OD, 400 MHz): 1.24 (s, 9H), 1.34 (t, 6H), 1.44 (s, 3H), 3.08 (dd, 2H), 4.29 (q, 4H), 5.88 (dd, 2H), 7.19–7.25 (m, 3H). MS (ESI) m/z 485.32 (M+H+)

Sources & evidence

ORD record: ord-333bf7016fd6402cbfa2b60ebf5e4cc5
Source dataset: uspto-grants-2006_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07101912B2

Reaction notes

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