1(3H)-Isobenzofuranone, 3-bromo- → HCID 69584922, compound

HRID 2212444Notes

Reaction equation

HRID 2212444 reaction equation
[C:1]([O:4][CH2:5][O:6][C:7](=[O:21])[C:8]([NH:19][NH2:20])([CH3:18])[CH2:9][C:10]1[CH:15]=[CH:14][C:13]([OH:16])=[C:12]([OH:17])[CH:11]=1)(=[O:3])[CH3:2].BrC1[C:32]2[C:27](=[CH:28][CH:29]=C[CH:31]=2)C(=O)O1>>[O:3]=[C:1]1[C:2]2[C:29](=[CH:28][CH:27]=[CH:32][CH:31]=2)[CH:5]([O:6][C:7](=[O:21])[C:8]([NH:19][NH2:20])([CH3:18])[CH2:9][C:10]2[CH:15]=[CH:14][C:13]([OH:16])=[C:12]([OH:17])[CH:11]=2)[O:4]1

Participants

3

Reactant 2

HCID 962181(3H)-Isobenzofuranone, 3-bromo-HCID 69584946HCID 69584946, compound

Product 1

HCID 69584922HCID 69584922, compound

Procedure

Following the procedure for preparation of compound 104, and substituting bromomethyl acetate with bromophthalide, provided the title compound 122 as a mixture of diastereomers. MS (ESI) m/z 359.03 (M+H+).

Sources & evidence

ORD record
ord-126b02326e8547bfb4d0b8263801330e
Source dataset
uspto-grants-2006_09
Patent number
US07101912B2

Reaction notes

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