HCID 86594120, compound → HCID 69584869, compound

Participants

Reaction Steps

A solution of compound 230 (441 mg, 1 mmol) in 1:1 (v/v) dichloromethane and trifluoroacetic acid was stirred at room temperature for 8 h (monitored by LC/MS). After removing the solvent under reduced pressure at room temperature, the residue was purified by preparative LC/MS technique to afford 165 mg (58%) of the title compound as a light yellow solid. 1H NMR (400 MHz, CD3OD): δ1.39 (3H, s), 2.93 (2H, m), 4.56 (1H, d), 4.75 (1H, d), 6.50 (1H, dd), 6.60 (1H, d), 6.67 (1H, d). MS (ESI) m/z 285.26 (M+H+) and 283.13 (M−H−).

Provenance & Evidence