HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → 1-Buten-1-one, 2-phenyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 2-Phenylbutyryl chloride | HCID 98173 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 1-Buten-1-one, 2-phenyl- | HCID 140690 | 70% |
Reaction Steps
A THF solution of 2-phenyl butyryl chloride (55 g, 0.3 mol) was added dropwise to a mixture of triethyl amine (91 g, 0.9 mol) in THF under nitrogen atmosphere. After one hour, precipitated triethyl amine hydrochloride was filtered. Filtrate was distilled under reduced pressure and EPK was obtained (60–70° C./4 mmHg). Amount obtained was 30 g (yield was 70%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07105272B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-986109b3452946a1b6a0eafff3d32155 |
| Source note | uspto-grants-2006_09 |