HuagongsheHuagongshe Chemistry Print Report · For research reference only
p-Toluenesulfonic acid → HCID 21955966, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Aniline | HCID 6115 | — |
| Reactant | HCID 21955958 | HCID 21955958 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 21955966 | HCID 21955966 | — |
Reaction Steps
The 4-[2-(2,2-dimethylethoxycarbonyl-amino)-4-phenyl-thiazol-5-yl]-2-iodo-pyrimidine (0.082 g, 0.17 mmol) is heated to reflux with aniline (0.032 g, 0.34 mmol) and dry p-toluene sulfonic acid (0.026 g, 0.136 mmol) in dry dioxane for five hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07105517B2 |
| Source dataset | uspto-grants-2006_09 |
| ORD ID | ord-3e8de0c68497478786a906f3b93a3444 |
| Source note | uspto-grants-2006_09 |