2-morpholin-4-ylmethyl-6-nitro-N-phenyl-benzamide → 2-amino-6-(4-morpholinylmethyl)-N-phenylBenzamide

Participants

Reaction Steps

A solution of compound 7 (0.3 g) and 10% Pd/C (30 mg) in methanol (35 mL) was stirred under hydrogen (1 atm) for 1.5 h. The mixture was filtered through a bed of CELITE® and the filtrate was concentrated to provide a yellow solid product, intermediate compound 2. ESI-MS m/z=312 (MH+).

Provenance & Evidence